The Gut-Brain Axis
The connection between the gut and the brain, known as the gut-brain axis, is a bidirectional communication system. This axis involves direct and indirect pathways between the central nervous system and the gastrointestinal tract, including neural, hormonal, and immune system signals. How Stress Impacts the Gut-Brain Axis-
Neurotransmitter Production
- Serotonin and GABA: The gut microbiome is involved in the production of neurotransmitters like serotonin and gamma-aminobutyric acid (GABA), which regulate mood and anxiety levels. Chronic stress can disrupt the balance of these neurotransmitters, leading to mood disorders and gastrointestinal issues.
- Source: Harvard Health
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HPA Axis Activation
- The hypothalamic-pituitary-adrenal (HPA) axis is activated during stress, leading to the release of cortisol, a stress hormone. Elevated cortisol levels can alter the gut microbiota composition, reducing beneficial bacteria and increasing harmful bacteria.
- Source: National Institutes of Health